Thursday, May 4, 2017

Biochemistry in Taste

Taste: You and Your Buds

Taste is one of our five senses, also referred to as gestation. Smell and taste are so complex they require special neurons sensitive to chemical substances to facilitate the senses. Although we are born with the ability to taste, the sense develops as we age, therefore babies and young children tend to dislike strong flavors such as onions and mustard. Taste buds are nerve endings on the tongue that sense only four sensations: bitter, salty, sour, and sweet (some scientist also believe there to be a fifth sensation; umami - savory). Texture, temperature, smell, and combinations of these sensations allow us to detect differences in the foods we eat. Taste is so influenced by smell that it is very important to our sense of taste to inhale and exhale as we eat or drink. Also, the sense of taste can be hindered by things such as zinc deficiency, smoking, a head cold or sinus problems, deficient sense of smell, or damage to certain parts of the brain. My dad was involved in a car crash as a teenager in which he suffered a laceration across his nose and mouth, severing the nerves to his nose. His injury made him unable to smell for a long time and even now, his sense of smell is limited. He is able to smell today because the only cells in the nervous system to be replaced when old ones are damaged or die are the neurons associated with smell and taste. Since his recovery my dad has developed a taste for strong flavors such as vinegar, citrus, and peppers. Texture is also a big factor for my dad now, he explains, "because there is not a lot of nuance in my taste, I'm very focused on the textures of the food I eat". For example (and much to my dismay) he does not like avocados but chocolate is his favorite food. 

Image result for taste in the brainThe Wolrd of Biology states, "taste begins when food or drink mix with saliva in the mouth and stimulate taste buds on the surface of the tongue, soft palate, pharynx, larynx, and epiglottis". I remember growing up believing the falsehood that specific areas of the tongue were designated for specific tastes. For instance, the taste buds receptive to sweetness were supposedly at the front, along the front sides were the taste buds receptive to salt, those further back were for sour flavors, and bitterness was detected by the far back taste buds. In 1901, D.P. Hanig, a German scientist, published the first "tongue map". Then in 1974 one of the first breakthroughs in taste research surfaced, and at this time scientists realized that the tongue map was a century old understanding that no one challenged. This breakthrough was realized by Virginia Collins. His research stated that individual taste buds are not even specifically sensitive to individual taste, instead "there are variations in sensitivity to the four basic tastes around the tongue" and he found that there are receptors that are sensitive to all tastes located around the tongue, on the soft palate, and in the epiglottis. These receptors have a neuronal response to combinations of bitterness, saltiness, sourness, and sweetness which are decoded in the brain, not in the mouth. Each one of us has 2,000-5,000 taste buds, which each contain 50-150 neuroepithelial cells. An action potential is initiated in these cells when a chemical stimulation occurs. These cells "interact through a complex system of electrical and synaptic responses with fibers within the central nervous system". Then these responses synapse to the medulla, the thalamus, and the postcentral gyrus.



Work Cited:
http://ic.galegroup.com/ic/scic/ReferenceDetailsPage/ReferenceDetailsWindow?disableHighlighting=&displayGroupName=Reference&currPage=&dviSelectedPage=&scanId=&query=&source=&prodId=&search_within_results=&p=SCIC&mode=view&catId=&u=dc_demo&limiter=&display-query=&displayGroups=&contentModules=&action=e&sortBy=&documentId=GALE%7CCV2431500598&windowstate=normal&activityType=&failOverType=&commentary=

http://www.livescience.com/7113-tongue-map-tasteless-myth-debunked.html

4 comments:

  1. I think this is so interesting; the science behind taste. How a person's taste can be altered by smoking, head damage or even something as common as a cold. Also, the complexity behind all the taste buds is truly a testament to the amazing biology of the human body; how there are so many in one's mouth and each one of them has at least 50 neuriepithelial cells. I too believed that areas of the tongue had specific taste buds to taste specific tastes like sweets or salty, but thanks to your post I know now that individual taste buds are not for specific tastes.

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  2. I find it very interesting that scientist were able to create a map of all our taste buds because people have such different likes and dislikes of certain foods. You mentioned smell played a role in how we taste, yet people try other peoples food all the time and are in the same relative area and therefore would have the same influence of smell. I wonder if there are any other actors of taste that have not been discovered yet that could cause people to taste things differently. Another thing i'm curious about is how our taste over time. Most people as they get older describe liking foods they once hated. In some cases it could just be that the food was just prepared differently, or were convinced by someone else they disliked something ,but is it possible that our taste buds could change over time?

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    1. Thanks for commenting Megan! I'll do my best to answer your questions.
      While everyone has the same taste receptors which can recognize the same five tastes (bitter, sweet, salty, sour and umami) the degree to which the receptors recognize these tastes differs from person to person. In other words, everyone has different sensitivities to different tastes. This explains why you may hate sour flavors like lemon, in which case your taste receptors would be more sensitive to sour, while your friend may have weak sour receptors and love lemon. These differing sensitivities probably arose from evolutionary pressures in different parts of the world. For example, studies show people from malaria-infested parts of the world tend to carry a gene that makes them less sensitive to some bitter compounds, specifically those that contain cyanide and cyanide (ingested at low levels) fights malarial parasites.
      As for your question about taste changing over time, it's not so much about our actual taste buds and receptors changing as the quantity of them changing over time and how that affects our overall sense of taste. Our senses of taste develop through the years because as babies we are born with A LOT of taste buds (that's why babies don't like strong flavors) and over time taste buds die then we become more open to a variety of tastes. A taste buds' lifespan is estimated to be 10 days so taste buds are in fact the only cells in the nervous system to be replaced when old ones are damaged or die; however, as we grow older less taste buds are able to be replaced. The quantity of taste buds is another factor that affects sensitivity in taste so that explains why we tend to like different things as we age.

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  3. I find it amazing that the only nerve cells that can be replaced are ones that deal with taste and smell. I never knew that before. I also was surprised to hear that the belief that different parts of your tongue taste different flavors was wrong. I certainly believed it to be true. Learning that there are so many cells that have to do with taste was mind blowing. I had heard that smell affected taste, and that having a stuffy nose affected it too, but I never know that so many other things also affected the way foods taste. I really enjoyed reading your post Emma. It was very informative.

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